| 产品介绍 |
Enalaprilat Dihydrate是一种新型血管紧张肽转化酶(ACE)抑制剂，IC50为1.2 nM。 |
| 别名 |
依那普利拉二水合物;2,4-二氯苯基-2-(-1H-咪唑)乙醇;(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid;Vasotec;Enalapril |
| 生化机理 |
Enaprilat is the active metabolite of the compound Enalapril. Enalapril is an ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. The compound is reported to be converted to the active form, Enalaprilat , through hepatic hydrolysis. Enalapril downregulates the expression of IL-β, IL-6, and NK-κB. Enalaprilat dihydrate is an activator of bradykinin B1 R. |
| 备注 |
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor withIC50 of 1.94 nM. |
| 应用 |
An active metabolite of the ACE inhibitor, Enalapril. |
